NEWS
Steve
Ley is awarded the 2009 Tetrahedron Prize
WHIFFEN COMMUNICATIONS (Group amd alumni only)
May
2009
LATEST PUBLICATIONS
Pd-EnCat
TPP30 as a Catalyst for the Generation of Highly Functionalized
Aryl- and Alkenyl-substituted Acetylenes via Microwave Assisted
Sonogashira type Reactions
J. Sedelmeier, S.V. Ley, H. Lange and I.R. Baxendale, Eur.
J. Org. Chem., 2009, 4412.
Enantioselective
Synthesis of the Lyngbouilloside Macrolactone Core
D. Webb, A. van den Heuval, M. Kögl and S.V. Ley, Synlett,
2009, 14, 2320.
Cancer,
Chemistry, and the Cell: Molecules that Interact with the Neurotensin
Receptors
R.M. Myers, J.W. Shearman, M.O. Kitching,
A. Ramos-Montoya, D.E. Neal, S.V. Ley, ACS Chem. Biol.,
2009, 4, 503.
Development of Fluorination Methods using Continuous-Flow Microreactors
M. Baumann, I.R. Baxendale, L.J. Martin and S.V. Ley, Tetrahedron,
2009, 65, 6611.
Total
Synthesis of the Potent Antifungal Agents Bengazole C and E
A. Enríquez-Garcia and S.V. Ley, Coll. Czech.
Chem. Comm., 2009, 74, 887.
LAB
LETTERS
Problems
Set by
Dr David France (11 Nov 2009)
Synthesis
of Chlorosulfolipids by
Daniel Salinger (11 Sept 2009)
C20-Diterpenoid Alkaloid Anthriscifolmine D by
Sarah Harding (21 Aug 2009)
Exercises on Guanacastepene
E by
Dr Georg Wuitschik (19 June
2009)
Some Stereoelectronic Considerations by
Dr Matt O’Brien (15 May
2009)
Friday 13th Synthesis Discussion by
Dr Colin Pearson (13 February 2009)
Phosphorus & Sulfur Blind Lab Letter byJames
Shearman (January 2009)
Movember's Lab Letter by
Jane Jin (26 November 2008)
October's Lab Letter
by Alex Oelke (31 October 2008)
July Synthesis Discussion (Cortistatin A) by
Dr Ross Denton (4 July 2008)
May
Questions
by
Dr Antoine Francais (16 May 2008)
April
Exercises by Dr Alvaro Enriquez (11 April 2008)
Leap
Year Puzzle by Dr Christoph Tzschucke (29 Feb 2008)
New
Year Exercises by
Alejandro Dieguez-Vazquez (25 Jan 2008)
LINKS
Not
Voodoo by Alison Frontier
Natural
and Unnatural Amino Acid Abbreviations MEROPS
Peptidase Database
The artwork for this year's Research Synopsis (and our group
web page) has been created by one of our post-docs.
'The Great Work’ by Matthew O'Brien acrylic on
canvas board, 2008 © Matthew O'Brien 2008
The painting is an abstract depiction of azadirachtin, whose
synthesis was recently completed by the Ley group. The culmination
of over 2 decades of work, the project represents a herculean
struggle which was only made possible by the great physical
and intellectual efforts of those involved. As the painting
attempts to portray, the complex and challenging nature of this
molecule (and others) requires and inspires a high degree of
creativity and imagination in the mind of the chemist.
Updated on
Thursday 26 October 2009